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Breakthroughs in Sickle Cell Anemia

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Researchers are making landmark breakthroughs in sickle cell research - Jose Mercado Sickle cell Anemia is a genetic disease carried by a recessive gene where the red blood cells malform and become sickle or crescent shaped causing red blood cells to die prematurely. This can pose a number or problems regarding not only quality of life, but also surgical complications, and injury prevention due to fragility.  Since 1948 the National Institute of Health (NIH) has been working to improve clinical  care and advancing the understanding of Sickle Cell       Some of the pioneering discoveries NIH has made are in the departments of  NHLBI Multicenter Study of Hydroxyurea  which demonstrated a medication called hydroxyurea reduced episodes of spontaneous pain in over 1/2 of severely affected adults with sickle cell disease. Another landmark in the war against Sickle Cell was the   Sickle Cell Disease Treatment with Arginine Therapy or (STArT) fo...

Why Does Sickle Cell Anemia Primarily Affect African Americans? by Malika Jones

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        SCA the Silent African American Killer Introduction Anyone is susceptible to inheriting sickle cell anemia (SCA) because it is a genetic disease. However, according to Solovief et al. (2011), sickle cell anemia is most common among African Americans. Based on such considerations, we aim to provide an overview of the research on why SCA primarily affects African Americans, which is essential for future research and studies. For this study, we evaluated scholarly reviewed articles to answer the question: Why does sickle cell anemia primarily affect African Americans? SCA in African Americans In a study conducted by Solovieff et al. (2011), they compare the ratio of sickle cell anemia in African Americans relative to Black Africans and Caucasians. They used a sample size of 1,810 African Americans with SCD, African Americans without SCD, and various Black African and Caucasian European populations, as seen in Table 3 (Solovieff et al., 2011). Conclusion This st...

Sickle Cell Anemia Data and Statistics By: Jacqueline George

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  Sickle Cell Anemia Data and Statistics By: Jacqueline George          Sickle Cell Anemia in the United States Sickle Cell Anemia primarily affects approximately 100,000 Americans.  Sickle Cell Anemia occurs among about 1 out of every 365 Black or African-American births.  About 1 in 13 Black or African-American babies is born with sickle cell trait (SCT)   Mortality Sickle cell-related death among Black or African-American children younger than the age 4 has decreased by 42% percent from 1999 through 2002.  Decreased by: 68% at age 0 through 3 years old  39% at age 4 through 9 years old 24% at age 10 through 14 years old.  Mortality among children with Sickle Cell Disease Identified by Newborn Screening during 1990-1994 California, Illinois, and New York.  By the end of 1995, in California and Illinois cumulative mortality rate was 1.5 per 100 African Ameri...

What is Sickle Cell Anemia? by Isabel Lawrence

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What is Sickle Cell Anemia? Sickle cell anemia is an incurable disease that affects the shape of blood cells. Usually, blood cells are round and bendable, so they can easily fit through blood vessels, but with sickle cell disease, blood cells are a rigid half moon shape. This can cause the blood cells to get stuck easier in blood cells, which can cause blockage and restrict blood flow.   Is there a cure? There is no cure for sickle cell anemia. Because it affects the shape of blood cells, this is not something easily cured. Doctors have tried to find a way to fix the blood cells, but so far no significant progress has been made. A major breakthrough in the scientific community would have to be made in order to change something this drastic about the human body. Symptoms? People who live with sickle cell anemia experience extreme bursts of pain. The main cause of this is the irregular shaped blood cells getting stuck in blood vessels and creating a blockage. Sometimes, the pain can ...